Whilst low-depend MBL rarely progresses to CLL, large-depend MBL progresses to CLL necessitating therapy in a rate of one% to 2% annually. Large-count MBL is distinguished from Rai 0 CLL dependant on whether or not the B-cell rely is higher than or beneath five × 109/L. Whilst people with both equally high-depend MBL and CLL Rai stage 0 are at ele